Plague 99

Plague 99 is a 2000 American animated fantasy film directed by Mark Dindal, written by Elana Lesser and Cliff Ruby, based on the 1989 novel of the same name by Jean Ure and produced by Timothy Campbell. The film stars the voices of Ryan Philippe, Melissa Joan Hart and Edward Furlong. The film's score was composed by Steve Goldstein. The film also contains elements of two sequel novels, Come Lucky April and Watchers at the Shrine.

It was produced by New Line Animation and was released by New Line Cinema on August 11, 2000, and it grossed $394.6 million over a $52 million budget, making it the highest-grossing animated film of 2000, outlasting Paramount's George's Marvelous Medicine and Disney's Dinosaur.